Disease,von Willebrand's

《英文msh詞典》Disease,von Willebrand's
[入口詞] Disease,von Willebrand's
[主題詞] von Willebrand Disease
[英文釋義] Group of hemorrhagic disorders in which the von Willebrand factor (Factor VIII-related antigen) is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time,deficiency of factor VIII,and impaired platelet adhesion.